Inactivated Poliovirus Vaccine Protects Transgenic Poliovirus Receptor Mice against Type 3 Poliovirus Challenge
نویسندگان
چکیده
منابع مشابه
Excretion of wild-type and vaccine-derived poliovirus in the feces of poliovirus receptor-transgenic mice.
The emergence of circulating vaccine-derived poliovirus (cVDPV) strains in suboptimally vaccinated populations is a serious threat to the global poliovirus eradication. The genetic determinants for the transmissibility phenotype of polioviruses, and in particularly of cVDPV strains, are currently unknown. Here we describe the fecal excretion of wild-type poliovirus, oral polio vaccine, and cVDP...
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Given the progress already made towards the goal of global eradication of poliomyelitis LE (polio), the risk of paralytic poliomyelitis is changing in many geographical areas. Vaccination against polio will need to continue because of the threat of wild poliovirus importation. However, an increasing number of polio-free countries are determining that the risk of paralytic poliomyelitis associat...
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ژورنال
عنوان ژورنال: Journal of Infectious Diseases
سال: 1997
ISSN: 0022-1899,1537-6613
DOI: 10.1093/infdis/175.2.441